Automation
 
 
Desktop Alchemist
Crystal growth
Crystal mounting
Liquid handling

"Since the Alchemist has arrived at Sareum Ltd the optimisation of initial hits obtained from 96 well factorial screens has been more accurate and comprehensive. This makes the process of obtaining good diffracting crystals more reproducible and quicker".

--Marieke Lamers
Head of Protein Science
Sareum Ltd

 
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Desktop Alchemist
Alchemist
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BirdFeeder
BirdFeeder
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BirdFeeder

Desktop Alchemist™ fine screen maker

With this cost effective laboratory automation tool, complex fine screens can be set up in under 3 minutes, with an entire screen created in under 25 minutes. From intuitive and easy-to-use software, to industry leading dispense accuracy and precision across all viscosities, the Rigaku Desktop Alchemist delivers reproducible fine screens on your benchtop.

Proven technology for superior accuracy and precision

Built upon the industry standard Rigaku Alchemist platform, but with a compact footprint and price, the Desktop Alchemist offers the ability to dispense reagents from ethanol to 100% glycerol with unsurpassed accuracy and precision, ensuring reliable and repeatable results without wasting any expensive additives, detergents or chemicals. Employing time tested and patented Eppendorf® Combitips® Plus positive-displacement non-contact dispensers, in conjunction with Rigaku Tapper™ technology as part of the unique patented BirdFeeder™ assembly, ensures that the correct volume is dispensed — regardless of the density or viscosity of the liquid — down to 1 μl with a total CV of less than 2%.

Built in stock solution storage and management

Solving the stock solution storage and management problem, the Desktop Alchemist CrystalTrak™ database holds thousands of stock chemicals that can be added or removed from the 26-position deck in a matter of seconds using barcoded BirdFeeder assemblies. Rigaku BirdFeeders then provide one aspirate with multiple dispenses — in a volume range of 1 μl to 10 ml — directly into VDX, Linbro or Nextal plate formats. Delivering custom screens without pumps and tubing, BirdFeeder technology provides self-contained liquid dispensing and individual stock solution management, with barcode tracking, individual syringes to assure against cross contamination, and integral long-term storage, all in one revolutionary design.

Software-guided fine screen production

Included with every Desktop Alchemist, CrystalTrak™ is a relational database application that simplifies and aids in the crystallization process by providing tools that enable users to greatly improve crystallization trial productivity with minimal user intervention, design well-targeted experiments, efficiently use protein samples and set up reproducible optimization experiments. CrystalTrak enables users to create crystallization screens simply and easily, allowing the setup of any type of gradient and then performing all the calculations and pipetting automatically.

Features and benefits

  • Tapper™ technology enables dispensing down to 1 μl with a total CV of less than 2%
  • Fast and easy to set up
  • Holds up to 26 barcoded stock solutions in patented BirdFeeder containers
  • No pumps, no tubing, no cross-contamination and no chemical waste
  • Consistent, precise and accurate liquid dispensing in a volume range of 1 μl to 10 ml
  • Non-contact, positive displacement pipetting
  • One aspirate, multiple dispenses
  • Stock usage tracking
  • Multiple BirdFeeder sizes and syringe sizes
  • Reliable storage of chemical stock in BirdFeeders
  • Easy change of stock solutions
  • Interchangeable plate nest adapters enable dispensing into SBS, Linbro and Nextal footprint plates