FR-E+ SuperBright™

Beamline data quality with the world's brightest home laboratory X-ray source
4x10¹¹ X-rays/sec/mm²

The Rigaku FR-E+ SuperBright is the most intense home laboratory X-ray source available today for macromolecular crystallography, providing brightness exceeding some second generation bending magnet synchrotron beamlines.

• Work on small and poor quality crystals at home
• Minimize travel to the synchrotron
• Improve your workflow by removing the bottleneck of remote data collection
• Improved filament life increases your productivity
• Phase at home—optional dual wavelength anode increases your experimental flexibility
• Proven productivity of Rigaku X-ray sources—88% of the HomeLab structures deposited in the PDB in 2006 were collected on a Rigaku X-ray source

Brightest X-ray source 

Producing unrivalled intensities of 4x10¹¹ X-rays/mm²/sec, this new synchrotron-class generator produces more than three times the flux of the closest competitive instrument. This advantage is made possible by advances in anode cooling and multilayer technology. Such a dramatic increase in performance is beneficial for all aspects of in-house crystallographic research, from exceptional data quality for very small and poor quality crystals to an overall enhancement of research productivity.

Optimized for small crystals

In addition to having the brightest X-ray beam, the FR-E+ SuperBright microfocus rotating anode X-ray source features a true 70 μm diameter circle focal spot, the smallest available in a rotating anode design. This allows the FR-E+ SuperBright to deliver a small and intense beam that is ideally suited to the tiny crystals typically encountered in current structural biology research.

Dual wavelengths for phasing

The FR-E+ SuperBright is the only rotating anode laboratory X-ray generator featuring dual wavelengths. Rigaku has developed a dual wavelength (copper/chromium) source that enables enhanced home lab single wavelength anomalous diffraction (SAD) phasing while retaining traditional data collection capabilities. Chromium radiation (2.29 Å) doubles the available anomalous signal from elements such as S, Ca and Se as compared to the signal available with copper radiation (1.54 Å). This enhanced signal opens new possibilities in phasing for macromolecular crystallography leading to de novo protein structure determinations that were previously not possible.

»» Learn more about Cr-SAD phasing

Features

• Highest flux of any microfocus rotating anode X-ray generator
• Smallest focal spot size of any rotating anode X-ray generator (70 μm diameter circle)
• Small beam provides greater flux density and less background for small samples
• Increases laboratory throughput by allowing for shorter exposure times and faster data collection
• Collect full data sets on samples where only low-resolution reflections were seen on a standard system
• Screen crystals where no diffraction is seen using a conventional rotating anode or sealed tube source
• Choice of anode materials: Cu, Cr, Mo, Cu/Cr, Cu/Co
• Computer controlled wavelength selection for dual wavelength anodes
• Definitive source for macromolecular crystallography where long-wavelength SAD phasing is critical to success
• Existing FR-E+ SuperBright systems are field upgradeable to dual wavelength
• Provides the highest flux when integrated with VariMax™ optics
• The X-ray generator of the Ultimate HomeLab™.
  

The FR-E+ SuperBright is the brightest microfocus rotating anode generator available. With the dual wavelength option, you can collect more data at home with the highest flux and two wavelengths.