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Fast SAXS Data Collection with the BioSAXS-2000 and HyPix-3000 HPAD

AppNote BX004 Biological SAXS on the BioSAXS-2000 with HyPix-3000 hybrid photon counting detector


Rigaku Oxford Diffraction's popular home lab Small Angle X-ray Scattering (SAXS) system is a two-dimensional Kratky camera called the BioSAXS-2000. The BioSAXS-2000 includes a double-bounce confocal optic with a large capture angle and thus provides more flux at the sample position, which means better signal to noise and faster experiments. Unlike other Kratky systems that use line focus sources, the BioSAXS-2000 uses a point focus source and confocal optic with the focal point of the optic at the surface of the detector so that data do not require any desmearing. The BioSAXS-2000 now features the Rigaku HyPix-3000 hybrid pixel array detector with 100 x 100 μm2 pixels (40% smaller than the PILATUS 3R 100K) for better spatial resolution in SAXS profiles. All together, these features lead to high quality SAXS data from the BioSAXS-2000.

SAXS products from Rigaku

A customized single crystal X-ray diffraction system that has the capabilities of utilizing both ports of a rotating anode X-ray source.

Small and wide angle X-ray scattering instrument designed for nano-structure analyses

Small and wide angle X-ray scattering instrument designed for nano-structure analyses

A modernized 2D Kratky system that eliminates data corrections required of traditional systems

A bespoke, extremely high-flux diffractometer with custom enclosure and the flexibility to utilize both ports of the rotating anode X-ray source.

Special CMF optic designed for SAXS instrumentation

Small angle X-ray scattering (SAXS) Kratky camera system.

Multipurpose products from Rigaku

Advanced state-of-the-art high-resolution XRD system powered by Guidance expert system software

Highly versatile multipurpose X-ray diffractometer with built-in intelligent guidance

High-performance, multi-purpose XRD system for applications ranging from R&D to quality control