Fig. 1 shows the X-ray diffraction pattern and qualitative analysis results obtained by measuring a sample in which corundum (weight 0.2 mg) was placed on a non-reflective sample plate. Intensity sufficient for conducting qualitative analysis was attained with a measurement time of 1 minute or less.
Fig. 2 shows the X-ray diffraction pattern for a trace amount of powder (weight 0.05 mg) obtained from a pill of Theodur, a type of medication for preventing asthma attacks. The qualitative analysis results confirmed the presence of anhydrous theophylline (the active ingredient) and lactose (the excipient). In this way, it is possible to quickly obtain the X-ray diffraction patterns necessary for identification, even with only a tiny amount of sample.
Apparatus condition:
MiniFlex600 (F.F tube 40 kV, 15mA), Detector: D/teX Ultra
Measurement condition:
Al₂O₃: Slit conditions: DS = 1.25°, SS = 8 mm, RS = 13 mm, Incident side and receiving side Soller slit: 5°, Incident height limiting slit = 10 mm, Scan range: 2θ = 20 ~ 70°, Sampling step: 0.02°, Scan speed: 100° / min. (about 40 sec.) Pharmaceutical drug: Slit conditions: DS = 0.1 mm, SS = 8 mm, RS = 13 mm, Incident side and receiving side Soller slit: 5°, Incident height limiting slit = 2 mm, Scan range: 2θ = 5 ~ 30°, Step width: 0.02°, Scan speed: 10° / min. (about 3 min.)