Skip to main content

Automatic processing of a large synchrotron dataset

AppNote PX012 Single crystal synchrotron data processing


CrysAlisPro is a comprehensive crystallographic software package for data collection and data reduction on Rigaku Oxford Diffraction single-crystal X-ray diffractometers. With two dedicated user interfaces (CrysAlisPro PX for protein applications and CrysAlisPro SM for small molecule applications), the software is easily optimized for specific experiments. Also, CrysAlisPro is not limited to processing data collected on Rigaku Oxford Diffraction systems. Users can easily import and read data from many external detector formats including CCD, CMOS, hybrid pixel array detector (HPAD) and imaging plate detectors. Thus, users can take advantage of CrysAlisPro processing workflows and algorithms on most datasets, no matter what instrument was used for data collection, whether it be synchrotron data or data collected on an instrument from another manufacturer. In this application note, we show an example of data processing for a very large synchrotron dataset.

Protein crystallography products from Rigaku

A customized single crystal X-ray diffraction system that has the capabilities of utilizing both ports of a rotating anode X-ray source.

A microfocus sealed tube single crystal X-ray diffractometer that is low maintenance and perfect for screening and evaluating protein crystals.

A single crystal X-ray diffractometer with high-flux microfocus rotating anode X-ray generator and direct detection, HPC X-ray detector.

A versatile and high-flux dual-wavelength (DW) X-ray diffractometer with an HPC X-ray detector for multipurpose diffraction experiments

A leading provider of reagent kits, stock solutions, proteins, and accessories for protein researchers.

Small angle X-ray scattering (SAXS) Kratky camera system

User-inspired data collection and data processing software for small molecule and protein crystallography

Automated tool for performing in situ crystallography experiments on existing X-ray diffractometers

Robotic sample changer to provide unattended data acquisition, enhanced productivity and standardized workflow to your research environment.

A unique curved single crystal X-ray diffraction detector based on direct X-ray detection technology with the highest 2θ range at a single position available for the home lab.

Extremely low noise, air-cooled X-ray detector based on direct X-ray detection technology.

High-resolution X-ray detectors for X-ray diffractometers from DECTRIS

Automated crystal transport, orientation and retrieval robot

The smallest detachable motorized goniometer head on the market