3D structure of large biological molecules
This technique employs single crystal X-ray diffraction (SXRD) to unambiguously determine the three-dimensional structure of large biological molecules. The determination of such molecules gives researchers insight into biology and life at the molecular level. Given the importance of this research, Rigaku has been at the forefront in the development of a wide range of instrumentation related to various aspects of macromolecular crystallography.
One important application is structure-based drug design, a technique by which drugs are designed based on a knowledge of the three-dimensional structure of an enzyme’s active site.
Rigaku recommends the following products:
Fast, flexible single crystal X-ray diffractometer with the latest generation sources and HPC X-ray detectors, perfect for any crystallography lab
Single crystal X-ray diffractometer with high-flux microfocus rotating anode X-ray generator
Versatile and high-flux dual-wavelength (DW) X-ray diffractometer with HPC X-ray detector for multipurpose diffraction experiments
Low noise, sensitive, air-cooled X-ray detector for superior X-ray diffraction data quality
Low noise, sensitive, air-cooled X-ray detector for superior X-ray diffraction data quality
Low noise, sensitive, air-cooled X-ray detector for superior X-ray diffraction data quality
Systems
Versatile and high-flux dual-wavelength (DW) X-ray diffractometer with HPC X-ray detector for multipurpose diffraction experiments
Detectors
Low noise, sensitive, air-cooled X-ray detector for superior X-ray diffraction data quality
Automation products
Automated tool for performing in situ crystallography experiments on existing X-ray diffractometers
Automated tool for performing in situ crystallography experiments on existing X-ray diffractometers
Accessories
User-inspired data collection and data processing software for small molecule and protein crystallography