The nano3DX is ideally suited to the analysis of bone samples at submicron resolution. One of the important features of the nano3DX is the ability to look at large samples at high resolution. In the example below, an entire mouse fibula was analyzed with the nano3DX, the first time a whole bone analysis has been performed.
Parallel beam geometry and the ability of the nano3DX to obtain rapid high-contrast images allowed for the collection of the full tomogram of the bone from the proximal to distal ends. With each slice, the structures in the bone are clearly visible, including the softer cartilage at the proximal end. The scale bars are 50 μm long in each of the insets and the bone itself is approximately 12 mm long. The bone marrow, microvessels and osteocyte lacunae are clearly depicted.