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Advanced handheld Raman spectrometer

Material verification and authentication

Progeny™

Perform lab-quality analysis of the widest range of solids, powders, liquids and other substances with handheld Progeny. Designed to be customized and flexible for seamless integration into any work environment for:

  • Raw material identification of pharmaceutical, nutraceutical and cosmetic ingredients
  • Verification of trial materials, chemical, solvents and cell culture media
  • Authentication of finished products and anti-counterfeit prevention

Streamlining material ID workflow

Progeny is a technologically advanced portable Raman spectrometer, expertly designed for processes including incoming material receiving, the warehouse, clean room, laboratory analysis and mobile lab. With the push towards 100% inspection, Progeny handheld Raman enables users to reduce workflow steps and make immediate decisions. CompleteID software provides fast and simple PASS / FAIL results, helping to achieve leaner manufacturing processes and lower costs per analysis without compromising quality.

1064nm laser for superior Raman performance

Unlike other portable Raman spectrometers, Progeny successfully minimizes sample-induced fluorescence interference with the use of a unique 1064nm excitation laser for expanded positive material identification. Sample moisture content is not an issue either. Progeny handheld Raman spectrometer delivers the industry’s widest and most comprehensive range of raw material identification and finished pharmaceutical product authentication in a handheld, sealed platform.

Regulatory Compliance

Manufacturers must comply with rigorous requirements to ensure consistent production of safe and effective products. Progeny handheld Raman facilitates regulatory compliance by providing a complete IQ/OQ/PQ protocol package, unique and truly compliant 21 CFR Part 11 digital signatures and an integrated camera for barcode reading to ensure error free data entry.

Progeny is an FDA 1040, USP, EP, MHRA GMP approved technique.

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Features

By integrating Progeny into the development of new applications or adapting it to current workflows, you can expect the ability to:

  • Accurately analyze your materials through packaging
  • Minimize the learning curve with a smartphone inspired interface
  • Increase confidence in your material ID with unparalleled sensitivity
  • Measure a wide range of materials with interference-free data
  • Expand your data transfer flexibility (LIMS, wireless, and docking station)

Progeny represents the latest in handheld Raman spectroscopy with its use of 1064 nm laser excitation. Progeny delivers the greatest benefits to help streamline your workflow procedures, decrease costs, increase product quality, and bring products to market faster. This ultimately accelerates your return on investment, while meeting regulatory compliance.

Advanced Performance  
  • 1064 nm laser excitation to minimize fluorescence interference
  • Spectral resolution 8-11 cm⁻¹ reveals minor differences in similar material
  • Spectral range 200-2500 cm⁻¹ covers the most relevant molecular spectral features
  • Transmissive volume phase grating design for years of alignment-free operation
  • TE cooled InGaAS 512 pixel detector for high resolution results
User Control
  • 30-490 mW adjustable laser power in 5 mW increments to optimize analysis
  • 5 ms to 30 s adjustable exposure time in 5 ms increments for more accurate results
  • Adjustable focus nose cone to ensure analysis of materials through packaging
CompleteID™ Software
  • Administrator created workflow methods specific to material ensures accurate analysis
  • Rapid addition of new materials to your custom on-board library
  • Truly 21 CFR Part 11 compliant digital signatures
  • On-board barcode scanner for error-free sample information entry
Sophisticated Ergonomics
  • Optimal for one-handed operation: 29.9 cm x 8.1 cm x 7.4 cm (11.8 in x 3.2 in x 2.9 in) and weighing ~1.5 kg (3.5 lbs)
  • IP-68 rated ruggedized aluminum housing for maximum durability and minimization of cross-contamination
  • Large high resolution screen allows for high visibility in confined spaces and outdoors
  • Choice of user interface:
    • Smartphone-inspired touchscreen provides fast learning-curve
    • Softkey buttons for one-handed operation while wearing protective gloves
Unique Accessories
  • Docking station for easy data transfer to LIMS or Server
  • Adjustable focus vial adapter to accommodate your different vial sizes
  • Tablet adapter to accommodate different sized tablets and other sample types for increased flexibility
Additional Services
  • IQOQPQ document and on-site validation services
  • Performance qualification and recertification services
  • Raw Material Identification Standard Operating Procedures documentation
Other Specifications
  • Certifications: FDA 1040, 21 CFR, CE, ISO 9001:2008 Certified Manufacturing facility
  • Battery: 14.4V Li-ion, 3100mAH, > 5hrs
  • External battery charger: 100~240VAC, 50-60Hz, +18V DC, 2.5A
  • Operating temperature of 20 to +50°C intermittent, +40°C continuous
  • Warranty of 24 months

Progeny is not ITAR-restricted, though a U.S. Department of Commerce export license may be required for some countries.

Several accessories are available with Progeny handheld Raman to optimize your analysis of samples presented in varying sizes, shapes and forms.

Included:

Adjustable nosecone ships with each instrument. This user adjustable feature optimizes the laser focus to ensure analysis of substances within packaging. It easily attaches to the front of the unit and is secured with a thumb screw.
Vial holder allows the user to adjust the sample position to optimize the laser focus for different sized vials. It attaches to the front of the unit and secured with a thumb screw. Progeny accessory

Optional:

Docking station expands data transfer portability. Quickly upload records to your LIMS or server. Transfer custom libraries to multiple units while charging the battery. Progeny accessory
Bottle adapter forms to bottles of different sizes and shapes. It snaps onto the nosecone. Progeny accessory
Tablet/universal adaptor can be used to hold samples of varying sizes including pills, capillary tubes, vials and small plastic packets. The tablet holder easily snaps onto the adjustable base adapter Progeny accessory

Progeny applications

cGMP, Regulatory Compliance and Brand Protection

Counterfeit pharmaceutical products are a growing global problem and a concern for both manufacturers and consumers. The global trade in counterfeit goods is booming, with a 2007 report from the Organization for Economic Cooperation and Development (OECD) putting a value of counterfeit goods crossing international borders at more than $250 billion.

Modern & Portable Laboratory

Today’s laboratories are being built and redesigned to promote workflow efficiency and not constrain workers and their activities. As technology continues to advance, large and outdated equipment is being replaced with smaller and more advanced instrumentation. Traditional benchtop units limit the flexibility of modern laboratories to adopt a collaborative and interdisciplinary approach to data collection and analysis.

Streamlined Raw Material Identification

The globalization of the pharmaceutical supply chain and push towards 100% material inspection has led to a significant increase in the demand for cost effective, efficient and regulatory compliant methods for raw material identification (RMID) and chemical verification. Strict quality assurance and quality control measures are more important than ever to ensuring the safety and efficacy of products before reaching consumers.

Progeny applications

Analysis of Dietary Supplements, Nutraceuticals, and their Raw Materials with Handheld Raman

To demonstrate the advantages of using a 1064 nm analyzer, the identification of a dietary supplement ingredient – vanadyl sulfate – was attempted with both handheld 785 nm and 1064 nm excitation Raman spectrometers.

Request a PDF copy of this report.

Aseptic Identification of Polysorbates using Handheld Raman

A feasibility study was performed to determine if polysorbate 20 and polysorbate 80 from three different vendors could be identified via analysis through their original, amber bottle packaging.

Request a PDF copy of this report.

Drug Product Identification Using Handheld Raman

A collaborative study was performed in conjunction with Pfizer Inc., Global Analytical Research and Development, by analyzing several different drug product (DP) formulations of (active pharmaceutical ingredient) API at different loading levels using Progeny.

Request a PDF copy of this report.

Herbal Materials & Natural Foods Analysis with Handheld Raman

To demonstrate the advantages of using a 1064 nm analyzer, the identification of two separate natural ingredients, turmeric and green tea powder was performed.

Request a PDF copy of this report.

On-Site Detection of Counterfeit Medicines & Healthcare Products with Handheld Raman

These analyses demonstrate the ability of Raman to distinguish authentic and counterfeit pharmaceutical and health care products quickly and easily with a robust field portable instrument.

Request a PDF copy of this report.

Pharmaceutical Excipients Identification with Handheld Raman

To demonstrate the advantages of handheld 1064 nm laser excitation, four common excipients used in many pharmaceutical products were analyzed using both 1064 nm and 785 nm

Request a PDF copy of this report.

Regulation of Raw Material Identification in Cosmetics

Twelve different types of commercially available essential oils were measured using handheld 1064 nm Raman.

Request a PDF copy of this report.

Learn more about how Progeny is different.



See how Progeny can improve efficiency.

Location Date Booth
ARABLAB Dubai, UAE Mar 12 2019 to Mar 14 2019
Kaohsiung Chemtech Kaohsiung, Taiwan Mar 29 2019 to Apr 1 2019
Analytica Vietnam Ho Chi Minh City, Vietnam Apr 3 2019 to Apr 5 2019
PharmaTech Taipei Taipei, Tawan Jun 19 2019 to Jun 22 2019
INTERPHEX 2019 Tokyo, Japan Jul 3 2019 to Jul 5 2019
BioTaiwan Taipei, Tawan Jul 3 2019 to Jul 5 2019
Lab Asia Kuala Lumpur, Malaysia Oct 15 2019 to Oct 17 2019
Taipei Instruments Expo Taipei, Tawan Oct 25 2019 to Oct 28 2019
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