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Winter 2017, Volume 33, No. 1

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Winter 2017, Volume 33, No. 1

The 2016 Nobel Prize in Physiology or Medicine

Akihito Yamano and Joseph D. Ferrara

The Nobel Prize in Physiology or Medicine was awarded to a Japanese scientist for the second year in a row for 2016. The laureate is Professor Yoshinori Osumi of the Tokyo Institute of Technology who received the award for the discovery of autophagy. Generally speaking, knowledge of autophagy is limited...

In situ microscopic structural investigations with a three-dimensional X-ray microscope: nano3DX

Kazuhiko Omote, Yoshihiro Takeda, Raita Hirose and Joseph D. Ferrara

It is well known that X-rays can penetrate opaque objects and show the internal structure without destroying the object. Thus, X-rays are widely used for medical imaging, security and industrial inspection to name a few examples. In addition, X-ray computed tomography (CT) is a powerful technique for visualizing internal structure...

Introduction to single crystal X-ray analysis XI. Crystallization of proteins —Crystallizability evaluation using BioSAXS—

Akihito Yamano

The principle problem in single crystal X-ray analysis is the so-called “phase problem”; however, in the current situation in which various measurement devices, synchrotron radiation facilities and sophisticated software have become available, the largest bottleneck in practice is the acquisition of single crystals, that is, crystallization of the substance to...

Sample preparation for X-ray fluorescence analysis VII. Liquid sample

Takao Moriyama and Atsushi Morikawa

We have discussed about the feature of X-ray fluorescence analysis (XRF) which is quick and nondestructive analysis of liquid, solid and powder sample in the previous issues. In this paper, analysis examples of liquid samples are shown. Careful attention is required for handling of liquid sample, because there are many...

Thermogravimetry / differential thermal analyzer with sample observation attachment

TG-DTA is a thermal analysis technique that measures the weight change of a sample (thermogravimetry, TG), and endothermic and exothermic reactions based on the difference in temperature between the sample and a reference (differential thermal analysis, DTA) during a programmed temperature change. It can measure the weight changes associated with...