- Faster, accurate data collection due to high-speed kappa goniometer, high-flux rotating anode X-ray source, fast, low-noise X-ray detector, and highly optimized instrument control software.
- Improve your ability to investigate small samples due to the increased flux from the rotating anode X-ray source as well as the extreme low-noise of the HyPix X-ray detectors. Noise free images mean you can count longer for weakly diffracting crystals without a loss in data quality arising from detector noise.
- Highest level of user safety with multiply redundant electromechanical safety circuits built into the ergonomically designed radiation enclosure.
- Minimize your downtime by utilizing built-in online diagnostics and troubleshooting to diagnose and fix almost all problems without a site visit.
- Automatically solve structures and determine what your sample is in a few seconds before committing to a full dataset by using the “What is this?” feature.
- Increased data collection speed due to the increased flux of the X-ray source.
- Enhance your ability to resolve large unit cells, twins or incommensurate lattices when you select the optional motorized variable beam slit in order to alter divergence to adapt the source to your sample’s requirements.
High flux rotating anode X-ray diffractometer
A powerful and fast system for single crystal X-ray diffraction analysis
The XtaLAB Synergy-R was designed to address the increasing need to investigate smaller and smaller samples in crystallographic research. Tightly integrating a PhotonJet-R microfocus rotating anode X-ray source with a high-speed kappa goniometer and a solid state pixel array HPC detector creates a single crystal diffractometer that produces up to 10 times the flux as compared to a PhotonJet-S microfocus sealed tube source. The increase in flux allows you to look at much smaller crystals than before and as a side benefit it provides increased data collection speed for normal sized crystals. The system can be equipped with your choice of HPC hybrid photon counting detectors, the HyPix-6000HE or the curved, large theta coverage HyPix-Arc 150°.
The PhotonJet-R comes from the same pedigree as the MicroMax-007 HF, of which there are well over 1000 units in use around the world. The PhotonJet-R X-ray source applies the lessons learned over the development and lifetime of the MicroMax™-007 rotating anode to produce a new generation, high performance rotating anode source. With the source mounted directly onto the goniometer the XtaLAB Synergy-R provides a stable and robust solution which ensures consistently high performance. Confocal optics, designed by Rigaku Innovative Technologies, offer a high-brilliance X-ray beam and the optional continuously variable slit assembly gives the user the ability to adjust high brilliance versus low divergence depending on the needs of the sample being studied.
The PhotonJet-R source was designed with reliability in mind. Clever Rigaku engineering makes filament changes easy, like swapping a printer cartridge, with no need to realign the source each time. Scheduled maintenance involves one annual visit from a Rigaku engineer, as with all XtaLAB Synergy diffractometers, and typically takes 1-2 days. With the anode exchange program, you get the benefit of rotating anode power with the convenience of sealed tubes.
Where overlapping peaks are a concern, e.g. large unit cells, twins or incommensurate lattices, high beam divergence is undesirable. On the PhotonJet-R source, a software controlled, motorized variable beam slit is available as an option to alter divergence to adapt the source to your sample’s requirements. For those samples where intensity matters most, the slit can be fully opened giving the highest flux. For those where peak sharpness and overlap are factors, the beam can be limited to a divergence anywhere between 1 to 10 mrad.
Rigaku’s own HyPix family of HPC detectors use solid state pixel array technology to enable direct X-ray photon detection and counting. Direct X-ray photon detection means that X-ray photons are counted instantaneously as they arrive at the detector. There is no conversion to visible light by a scintillator so the energy of the photon can be assessed at moment of detection. This leads to essentially noise free images. The HyPix detectors feature a 100 Hz frame rate which allows for data fine slicing even at the fastest goniometer speeds. The HyPix detectors incorporate dual counters enabling several modes of operation. Rapid alternating counter electronics (RACE) technology enables the 100 Hz zero dead time mode, ensures that no pixel is blind for more than a few nanoseconds during exposure to X-rays. The high dynamic range mode combines the counters to offer a massive 31-bit counter depth. Dual thresholding offers differential modes and selective signal suppression.
The XtaLAB Synergy-S comes complete with CrysAlisPro, our user-inspired data collection and data processing software for single crystal analysis. Designed around an easy-to-use graphical user interface, CrysAlisPro can be operated under fully automatic, semi-automatic or manual control. CrysAlisPro combines automated crystal screening, the fastest and most accurate strategy software available, concurrent data reduction and automatic small molecule structure solution. Visual feedback is provided for each step with clear, color-coded guidance so that both novices and experts can collect high-quality data in the shortest time possible.
AutoChem is the ultimate productivity tool for small molecule chemists, offering fast, fully automatic structure solution and refinement during data collection. Developed in collaboration with OlexSys Ltd (Durham University, UK), AutoChem works in conjunction with Olex² where more advanced structure solution and refinement functionality exists. AutoChem is seamlessly integrated within CrysAlisPro, and forms an integral part of our ‘What is this?’ feature. The ‘What is this?’ feature gives you structures quickly and ensures you are not wasting time collecting full datasets on known samples or starting materials. It is an alternative pre-experiment option, which is used to plan your full data collections.
Specifications and features
|Product name||XtaLAB Synergy-R|
|Technique||Single crystal X-ray diffraction|
|Core attributes||Microfocus rotating anode X-ray source diffractometer with hybrid pixel array detector and kappa goniometer|
|Detectors||HyPix-6000HE or optionally the large theta coverage HyPix-Arc 150°|
|X-ray Source||PhotonJet-R X-ray source with MicroMax™-007 rotating anode, which incorporates a new mirror design and new alignment hardware. Two target types are available (Mo or Cu)|
|Goniometer||Fast kappa geometry goniometer, which allows data collection scan speeds of up to 10°/sec|
|Accessories||Oxford Cryostream 800, Oxford Cobra, XtalCheck-S, High Pressure Kit, and Element Analyzer|
|Computer||External PC, MS Windows® OS|
|Core dimensions||1300 (W) x 1875 (H) x 850 (D) (mm)|
|Mass||600 kg (core unit)|
|Power requirements||1Ø, 200-230 V, 20 A|
The HyPix-Arc 150° is an optional, unique curved Hybrid Photon Counting (HPC) X-ray detector for single crystal diffraction applications.
The 800 Series Cryostream is the most robust, efficient and user-friendly liquid nitrogen based low temperature system available today. Specific features include a superior laminar flow system, meaning virtually zero risk of icing, extremely quiet running and a fast-start system resulting in a cool-down time to 100K of just 20 minutes.
The Oxford Cobra is the non-liquid nitrogen Cryostream. Combining the efficiency of a Cryostream with the advantages of a non-liquid system, the Cobra offers the ultimate solution for both macromolecular and small molecule crystallography.
The XtalCheck-S system includes software that facilitates both visual and diffraction imaging of crystallization experiments. With the XtalCheck-S system, one can easily survey many crystallization experiments by eliminating the need to harvest and cryo-cool samples. Moreover, one can perform serial crystallography experiments, by collecting data from multiple crystals, to achieve complete data sets that can be used for structure solution, as well as perform powder data collection from samples mounted in the crystallization wells.
Accommodating the vast majority of commercially available and custom high pressure cells the high pressure kit creates a sample space with an 8 cm diameter. It’s easy to switch between high pressure and standard mode and with powerful high-pressure software tools to aid with data analysis and processing, high pressure diffraction experiments have never been easier.
*Please check with your local sales person if your DAC is supported
The ELement ANalyzer is a state-of-the-art attachment that allows us to obtain qualitative information on elements in a single crystal at the same time as X-ray diffraction data collection for a single crystal structural analysis. By measuring the X-ray fluorescence spectrum emitted during X-ray diffraction experiments with the ELement ANalyzer, it becomes possible to perform elemental analysis on a single grain of crystal. The ELement ANalyzer can be used for confirmation the presence of central metal(s) in a mononuclear or polynuclear complex or solvent in a crystal for small molecule X-ray crystallography. There is a broad range of possible applications of the ELement ANalyzer in scientific fields.