What Is Handheld Raman Spectroscopy?
The ideal tool for raw material identification
Raman spectroscopy is an established vibrational technique that works by first exciting a sample with a laser. A small portion of this light undergoes “inelastic scatter” (also referred to as the Raman scatter or the Raman effect). The return signal is received and read by a detector, resulting in what is referred to as a Raman spectrum. The Raman spectrum contains a series of peaks that relate to features in the sample’s molecular structure. Each compound’s Raman spectrum is unique, and serves as a “chemical fingerprint” that can be used to identify an unknown compound, or a mixture of compounds. Onboard algorithms are used to match the sample’s spectral constituents to an extensive Raman spectral database to provide a positive identification of the sample.
Chemical detection systems based on handheld Raman spectroscopy are ideal tools for analyzing potentially hazardous samples, because unlike other handheld detection techniques, analysis can often be performed though packaging material, without disturbing the sample, which minimizes exposure to the operator. While handheld Raman-based chemical detectors have traditionally been developed using a 785 nm laser to excite the sample, this method is known to generate heavy fluorescence interference when trying to analyze colored materials.
For this reason, the use of handheld Raman based detection systems have historically been used primarily for identifying white powders and clear liquids, which are the least likely samples to produce fluorescence. While numerous pharmaceutical or laboratory-grade compounds exist as white powders and clear liquids, many real-world threats commonly encountered by military and first responder personnel are colored by impurities from crude synthetic processes, low grade precursors, or from intentionally added pigments and dyes such as those found in household products.
The Rigaku portfolio of handheld Raman analyzers are differentiated from traditional handheld and portable Raman systems because of their unique 1064 nm excitation technology. By utilizing 1064 nm laser excitation, the Rigaku Progeny, CQL Gen-ID, CQL Max-ID and CQL Narc-ID overcome fluorescence interference common to samples that are colored or in colored packaging.
Rigaku recommends the following products
CQL Max-ID
Offers features and benefits that maximize chemical threat analysis in safety and security applications
Learn moreCQL Gen-ID
A cost-effective solution for departments looking for targeted chemical threat analysis
Learn moreCQL Narc-ID
Provides presumptive identification of narcotics, precursor chemicals, and cutting agents
Learn moreProgeny
Handheld Raman for raw material identification and finished product authentication using 1064 nm Raman analysis.
Learn moreApplication notes
The following application notes are relevant to this technique
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RAD9150 - Identification of Fentanyl Precursors with Handheld 1064 nm Raman
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RAD9140 - Household Hazardous Material Identification using Handheld 1064 nm Raman
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RAD9130 - Narcotics Identification using Rigaku CQL Narc-ID Handheld Raman
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RAD9110 - Presumptive Field Testing for Narcotics, Explosives and Chemical Warfare Agents with Handheld 1064 nm Raman
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RAD9100 - Novel Psychoactive Substances (NPS) Identification using Rigaku Raman
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RAD9060 - Presumptive Identification of Xylazine - an Emerging Threat in Street Drugs
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RAD9040 - Combatting the Fentanyl Epidemic using Handheld 1064 nm Raman
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RAD9030 - Advanced 1064 nm Raman used to Counter Threats in Transportation Screening
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RAD9010 - Chemical Warfare Agent (CWA) Identification using Rigaku Handheld Raman Spectroscopy
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RAD9000 - Homemade Explosives Analysis
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RAD2093822 - Cell Culture Media Identification in Biopharmaceuticals
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RAD008 - Aseptic Identification of Polysorbates
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RAD007 - Herbal Materials andNatural Foods Analysis with Handheld Raman
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RAD006 - Pharmaceutical Excipients Identification with Handheld Raman
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RAD005 - Drug Product Identification
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RAD004 - Analysis of Dietary Supplements, Nutraceuticals, and their Raw Materials
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RAD003 - On-site Detection of Counterfeit Medicines and Healthcare Products with Handheld Raman
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RAD002 - Regulation of Raw Material Identification in Cosmetics
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2093805 - Polymorph Monitoring with the Rigaku Progeny 1064 nm Handheld Raman Analyzer
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20103570 - Analysis of Hand Sanitizer Products using Handheld 1064 nm Raman
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