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TOPIQ | Exploring the landscape of macromolecular solutions with SAXS

TOPIQ | Exploring the landscape of macromolecular solutions with SAXS

 

Small angle X-ray scattering (SAXS) is a useful technique for extracting structural information from biological samples in solution. Most biological SAXS samples are aqueous solutions with proteins present in low concentration. In other cases, it may be of interest to study macromolecules at high concentration, at high viscosity or at conditions in which macromolecules are expected to crystallize. In such cases, SAXS can still provide useful information about the inherent structure and phase of macromolecules. This presentation will describe experiments with both typical and non-typical macromolecular solution samples to illustrate the versatility offered by SAXS for macromolecular samples.

Presenter
Angela Criswell
Date/time (CDT)