Determine the three dimensional structure of molecules
Chemical or small molecule crystallography is a technique that employs single crystal X-ray diffraction (SCX) to unambiguously determine the three-dimensional structure of molecules. When molecules crystalize (think sugar) they form a three-dimensional regular arrangement of molecules. X-rays are diffracted by crystals and the diffraction pattern so created can be measured and analyzed to determine the atomic arrangements within the molecule being studied. The technique provides accurate and precise measurements of molecular dimensions in a way that no other method can approach. The technique may be applied to compounds of both chemical and biological interest, including new synthetic chemicals, catalysts, pharmaceuticals, and natural products. A frequent use is the identification of natural products, or of the products of synthetic chemistry experiments; however, detailed molecular geometry, intermolecular interactions and absolute configuration can also be studied. Some of the important information that can be derived from this technique include:
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Rigaku recommends the following products:
A benchtop single crystal X-ray diffractometer with the latest technology HPC X-ray detector, ideal for self-service crystallography.
Fast, flexible single crystal X-ray diffractometer with the latest generation sources and HPC X-ray detectors, perfect for any crystallography lab
Single crystal X-ray diffractometer with high-flux microfocus rotating anode X-ray generator
Versatile and high-flux dual-wavelength (DW) X-ray diffractometer with HPC X-ray detector for multipurpose diffraction experiments
Versatile and high-flux dual-wavelength (DW) X-ray diffractometer with HPC X-ray detector for multipurpose diffraction experiments
An upgradeable single crystal X-ray diffractometer for structural analysis of small molecule samples
Single crystal X-ray diffractometer with custom enclosure and flexibility for easy integration of accessory components
User-inspired data collection and data processing software for small molecule and protein crystallography
Low noise, sensitive, air-cooled X-ray detector for superior X-ray diffraction data quality
Low noise, sensitive, air-cooled X-ray detector for superior X-ray diffraction data quality
Low noise, sensitive, air-cooled X-ray detector for superior X-ray diffraction data quality
Low noise, sensitive, air-cooled X-ray detector for superior X-ray diffraction data quality