Introduction to X-ray analysis using the diffraction method
A scientific discipline, which investigates crystal structures by means of the X-ray diffraction method, is called X-ray crystallography or simply crystallography. It originated in a...
A scientific discipline, which investigates crystal structures by means of the X-ray diffraction method, is called X-ray crystallography or simply crystallography. It originated in a...
Quantitative phase analysis (QPA) using the X-ray diffraction technique is routinely employed to find weight ratios of individual component phases in a mixture. Techniques for...
Solid drugs taken orally are mixtures of active pharmaceutical ingredients (hereinafter referred to as “API”); agents such as excipients added as binders or diluents; and lubricants...
In the early stages of new drug discovery, the structure of small molecule hits resulting from compound screening is modified to derive leads (putative drug...
The phenomenon whereby a single substance exhibits multiple different crystal structures is known as crystal polymorphism; the structures are known as polymorphic forms. Many active...
Many Japanese pharmaceutical companies are now intensively investigating methods for inspection of starting materials. One of the reasons is the PIC/S (Pharmaceutical Inspection Convention and...
The analysis of metal impurities for pharmaceutical products such as harmful elements contained in the raw materials and residual catalysts in the manufacturing process is...